Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Neurog2  neurogenin 2   (Synonyms: Atoh4, bHLHa8, Math4A, ngn2)
Results	Reference
1	J:229226 Amaniti EM, Fu C, Lewis S, Saisana M, Magnani D, Mason JO, Theil T, Expansion of the piriform cortex contributes to corticothalamic pathfinding defects in Gli3 conditional mutants. Cereb Cortex. 2015 Feb;25(2):460-71
1	J:287136 Aslanpour S, Han S, Schuurmans C, Kurrasch DM, Neurog2 Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis. J Neurosci. 2020 Apr 29;40(18):3549-3563
1	J:173570 Asprer JS, Lee B, Wu CS, Vadakkan T, Dickinson ME, Lu HC, Lee SK, LMO4 functions as a co-activator of neurogenin 2 in the developing cortex. Development. 2011 Jul;138(13):2823-32
1	J:96233 Backman M, Machon O, Mygland L, van den Bout CJ, Zhong W, Taketo MM, Krauss S, Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon. Dev Biol. 2005 Mar 1;279(1):155-68
1	J:184000 Baubet V, Xiang C, Molczan A, Roccograndi L, Melamed S, Dahmane N, Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development. Development. 2012 Jun;139(11):1903-9
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:171429 Besse L, Neti M, Anselme I, Gerhardt C, Ruther U, Laclef C, Schneider-Maunoury S, Primary cilia control telencephalic patterning and morphogenesis via Gli3 proteolytic processing. Development. 2011 May;138(10):2079-88
1	J:160580 Borello U, Cobos I, Long JE, McWhirter JR, Murre C, Rubenstein JL, FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. Neural Dev. 2008;3:17
1	J:159104 Cai Z, Feng GS, Zhang X, Temporal requirement of the protein TyrosinePhosphatase Shp2 in establishing the neuronal fatein early retinal development. J Neurosci. 2010 Mar 17;30(11):4110-9
1	J:271140 Diacou R, Zhao Y, Zheng D, Cvekl A, Liu W, Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation. Cell Rep. 2018 Nov 27;25(9):2510-2523.e4
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:119663 Feng L, Xie X, Joshi PS, Yang Z, Shibasaki K, Chow RL, Gan L, Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina. Development. 2006 Dec;133(24):4815-25
1	J:305200 Fernandez V, Martinez-Martinez MA, Prieto-Colomina A, Cardenas A, Soler R, Dori M, Tomasello U, Nomura Y, Lopez-Atalaya JP, Calegari F, Borrell V, Repression of Irs2 by let-7 miRNAs is essential for homeostasis of the telencephalic neuroepithelium. EMBO J. 2020 Nov 2;39(21):e105479
1	J:147469 Flames N, Hobert O, Gene regulatory logic of dopamine neuron differentiation. Nature. 2009 Apr 16;458(7240):885-9
1	J:240473 Geng X, Acosta S, Lagutin O, Gil HJ, Oliver G, Six3 dosage mediates the pathogenesis of holoprosencephaly. Development. 2016 Dec 01;143(23):4462-4473
1*	J:79630 Gonzalez G, Puelles L, Medina L, Organization of the mouse dorsal thalamus based on topology, calretinin immnunostaining, and gene expression. Brain Res Bull. 2002 Feb-Mar 1;57(3-4):439-42
1*	J:293446 Han S, Dennis DJ, Balakrishnan A, Dixit R, Britz O, Zinyk D, Touahri Y, Olender T, Brand M, Guillemot F, Kurrasch D, Schuurmans C, A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis. Development. 2018 Oct 1;145(19):dev157719
1	J:298587 Hasenpusch-Theil K, Laclef C, Colligan M, Fitzgerald E, Howe K, Carroll E, Abrams SR, Reiter JF, Schneider-Maunoury S, Theil T, A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development. Elife. 2020 Aug 25;9:e58162
1	J:121744 Inoue T, Ota M, Ogawa M, Mikoshiba K, Aruga J, Zic1 and Zic3 regulate medial forebrain development through expansion of neuronal progenitors. J Neurosci. 2007 May 16;27(20):5461-73
1	J:194049 Johansson PA, Irmler M, Acampora D, Beckers J, Simeone A, Gotz M, The transcription factor Otx2 regulates choroid plexus development and function. Development. 2013 Mar;140(5):1055-66
1*	J:138815 Kawaguchi A, Ikawa T, Kasukawa T, Ueda HR, Kurimoto K, Saitou M, Matsuzaki F, Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis. Development. 2008 Sep;135(18):3113-24
1*	J:144373 Kinameri E, Inoue T, Aruga J, Imayoshi I, Kageyama R, Shimogori T, Moore AW, Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One. 2008;3(12):e3859
1	J:208421 Klimova L, Kozmik Z, Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Development. 2014 Mar;141(6):1292-302
1	J:99239 Kroll TT, O'Leary DD, Ventralized dorsal telencephalic progenitors in Pax6 mutant mice generate GABA interneurons of a lateral ganglionic eminence fate. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7374-9
1	J:84901 Kuschel S, Ruther U, Theil T, A disrupted balance between Bmp/Wnt and Fgf signaling underlies the ventralization of the Gli3 mutant telencephalon. Dev Biol. 2003 Aug 15;260(2):484-95
1	J:225435 Laclef C, Anselme I, Besse L, Catala M, Palmyre A, Baas D, Paschaki M, Pedraza M, Metin C, Durand B, Schneider-Maunoury S, The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor. Hum Mol Genet. 2015 Sep 1;24(17):4997-5014
1	J:122567 Lakhina V, Falnikar A, Bhatnagar L, Tole S, Early thalamocortical tract guidance and topographic sorting of thalamic projections requires LIM-homeodomain gene Lhx2. Dev Biol. 2007 Jun 15;306(2):703-13
1	J:166777 Lavado A, Lagutin OV, Chow LM, Baker SJ, Oliver G, Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol. 2010;8(8)
1	J:130851 Lavado A, Lagutin OV, Oliver G, Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon. Development. 2008 Feb;135(3):441-50
1*	J:270210 Loo L, Simon JM, Xing L, McCoy ES, Niehaus JK, Guo J, Anton ES, Zylka MJ, Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019 Jan 11;10(1):134
1	J:165487 Magnani D, Hasenpusch-Theil K, Jacobs EC, Campagnoni AT, Price DJ, Theil T, The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence. J Neurosci. 2010 Oct 13;30(41):13883-94
1	J:220860 Magnani D, Morle L, Hasenpusch-Theil K, Paschaki M, Jacoby M, Schurmans S, Durand B, Theil T, The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon. Hum Mol Genet. 2015 May 1;24(9):2578-93
1	J:328992 Manuel M, Tan KB, Kozic Z, Molinek M, Marcos TS, Razak MFA, Dobolyi D, Dobie R, Henderson BEP, Henderson NC, Chan WK, Daw MI, Mason JO, Price DJ, Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals. PLoS Biol. 2022 Sep;20(9):e3001563
1	J:183861 Marcos-Mondejar P, Peregrin S, Li JY, Carlsson L, Tole S, Lopez-Bendito G, The lhx2 transcription factor controls thalamocortical axonal guidance by specific regulation of robo1 and robo2 receptors. J Neurosci. 2012 Mar 28;32(13):4372-85
1	J:78037 Muzio L, DiBenedetto B, Stoykova A, Boncinelli E, Gruss P, Mallamaci A, Conversion of cerebral cortex into basal ganglia in Emx2(-/-) Pax6(Sey/Sey) double-mutant mice. Nat Neurosci. 2002 Aug;5(8):737-45
1*	J:102092 Muzio L, Mallamaci A, Emx1, emx2 and pax6 in specification, regionalization and arealization of the cerebral cortex. Cereb Cortex. 2003 Jun;13(6):641-7
1*	J:68840 Nakagawa Y, O'Leary DD, Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. J Neurosci. 2001 Apr 15;21(8):2711-25
1	J:285050 Ochi S, Imaizumi Y, Shimojo H, Miyachi H, Kageyama R, Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain. Development. 2020 Feb 26;147(4):dev182204
1*	J:119850 Oh S, Huang X, Chiang C, Specific requirements of sonic hedgehog signaling during oligodendrocyte development. Dev Dyn. 2005 Nov;234(3):489-96
1*	J:174498 Oldekamp J, Kraemer N, Alvarez-Bolado G, Skutella T, bHLH gene expression in the Emx2-deficient dentate gyrus reveals defective granule cells and absence of migrating precursors. Cereb Cortex. 2004 Sep;14(9):1045-58
1	J:92098 Petersen PH, Zou K, Krauss S, Zhong W, Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat Neurosci. 2004 Aug;7(8):803-11
1	J:154645 Pinto L, Drechsel D, Schmid MT, Ninkovic J, Irmler M, Brill MS, Restani L, Gianfranceschi L, Cerri C, Weber SN, Tarabykin V, Baer K, Guillemot F, Beckers J, Zecevic N, Dehay C, Caleo M, Schorle H, Gotz M, AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex. Nat Neurosci. 2009 Oct;12(10):1229-37
1	J:133489 Qiu F, Jiang H, Xiang M, A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors. J Neurosci. 2008 Mar 26;28(13):3392-403
1*	J:149737 Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ, The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511
1	J:224205 Segklia A, Seuntjens E, Elkouris M, Tsalavos S, Stappers E, Mitsiadis TA, Huylebroeck D, Remboutsika E, Graf D, Bmp7 regulates the survival, proliferation, and neurogenic properties of neural progenitor cells during corticogenesis in the mouse. PLoS One. 2012;7(3):e34088
1	J:84846 Seibt J, Schuurmans C, Gradwhol G, Dehay C, Vanderhaeghen P, Guillemot F, Polleux F, Neurogenin2 specifies the connectivity of thalamic neurons by controlling axon responsiveness to intermediate target cues. Neuron. 2003 Jul 31;39(3):439-52
1	J:81762 Stenman J, Yu RT, Evans RM, Campbell K, Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon. Development. 2003 Mar;130(6):1113-22
1	J:275375 Sun S, Zhu XJ, Huang H, Guo W, Tang T, Xie B, Xu X, Zhang Z, Shen Y, Dai ZM, Qiu M, WNT signaling represses astrogliogenesis via Ngn2-dependent direct suppression of astrocyte gene expression. Glia. 2019 Jul;67(7):1333-1343
1	J:191783 Teissier A, Waclaw RR, Griveau A, Campbell K, Pierani A, Tangentially migrating transient glutamatergic neurons control neurogenesis and maintenance of cerebral cortical progenitor pools. Cereb Cortex. 2012 Feb;22(2):403-16
1*	J:127119 Visel A, Carson J, Oldekamp J, Warnecke M, Jakubcakova V, Zhou X, Shaw CA, Alvarez-Bolado G, Eichele G, Regulatory pathway analysis by high-throughput in situ hybridization. PLoS Genet. 2007 Oct 19;3(10):1867-83
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1*	J:325555 Wang Y, Herzig G, Molano C, Liu A, Differential expression of the Tmem132 family genes in the developing mouse nervous system. Gene Expr Patterns. 2022 Jun 8;45:119257
1	J:171660 Winpenny E, Lebel-Potter M, Fernandez ME, Brill MS, Gotz M, Guillemot F, Raineteau O, Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells. Neural Dev. 2011;6:12
1	J:206964 Wu X, Gu X, Han X, Du A, Jiang Y, Zhang X, Wang Y, Cao G, Zhao C, A novel function for Foxm1 in interkinetic nuclear migration in the developing telencephalon and anxiety-related behavior. J Neurosci. 2014 Jan 22;34(4):1510-22
1	J:66590 Yun K, Potter S, Rubenstein JL, Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon. Development. 2001 Jan;128(2):193-205